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Endgames Case Review

An unusual cause of hypokalaemia

BMJ 2024; 384 doi: https://doi.org/10.1136/bmj-2023-077724 (Published 08 February 2024) Cite this as: BMJ 2024;384:e077724
  1. Bo Liu, consultant nephrologist,
  2. Cao Huang, gastroenterologist,
  3. Yunfei Pan, general practitioner,
  4. Jianping Yao, consultant endocrinologist
  1. Huzhou Central Hospital, Affiliated Central Hospital of Huzhou University, Affiliated Huzhou Hospital, Zhejiang University School of Medicine, China
  1. Correspondence to J Yao yjp1016{at}outlook.com

A man in his 50s was admitted to the endocrinology ward for persistently low potassium levels. One year previously, he had been admitted under the neurology department with a two year history of recurrent limb weakness. He had no known medical conditions or history of long term drug use. Physical examination revealed stable vital signs, no abnormalities on auscultation of the heart and lungs, grade 4 muscle strength in both lower extremities, and decreased tendon reflexes and muscle tone. Blood tests performed one year previously had indicated hypokalaemia, hypomagnesaemia, and hyperthyroidism (table 1), and he had received a diagnosis of hypokalaemic periodic paralysis and hyperthyroidism. The hyperthyroidism had improved after one year of treatment with iodine radiation therapy; however, his potassium level had remained low, and simultaneous oral and intravenous potassium supplementation had been ineffective. Results of tests conducted …

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