Intended for healthcare professionals

Analysis

Appendicectomy remains treatment of choice for patients with acute appendicitis

BMJ 2023; 382 doi: https://doi.org/10.1136/bmj-2022-074652 (Published 21 August 2023) Cite this as: BMJ 2023;382:e074652
  1. Abdullah K Malik, NIHR academic clinical fellow in general surgery12 3,
  2. Ailsa H Innes, core surgical trainee4,
  3. Lomalan Reddy, associate general practitioner5,
  4. Clara Munro, surgical registrar1,
  5. Alexander W Phillips, professor of oesophagogastric surgery and surgical education16
  1. 1Northern Oesophago-gastric Unit, Royal Victoria Infirmary, Newcastle upon Tyne, UK
  2. 2Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne
  3. 3Liver Unit, Freeman Hospital, Newcastle upon Tyne
  4. 4Department of Surgery, Queen Elizabeth Hospital, Gateshead, UK
  5. 5Saltaire and Windhill Medical Partnership, Bradford, UK
  6. 6School of Medical Education, Newcastle University, Newcastle upon Tyne
  1. Correspondence to: A K Malik abdullah.malik{at}nhs.net

Although many patients were safely managed with antibiotics during covid-19, Abdullah K Malik and colleagues argue that the associated risks and patient burden make surgery the best approach for appendicitis

Acute appendicitis is a common condition that almost all doctors will encounter at some point during their career. Until recently patients were usually treated surgically with an appendicectomy, with antibiotics used for those with prohibitively high perioperative risks because of comorbidities or an appendiceal mass. However, conservative management of acute appendicitis was advocated during the covid-19 pandemic because of concerns about aerosol formation during laparoscopic surgery and higher risk of morbidity and mortality in patients with covid-19.12 Further evidence has accumulated on the safety and effectiveness of antibiotics in adults with acute appendicitis.345678 This, together with greater use of computed tomography to identify complications, has shifted attitudes and led to antibiotic treatment becoming more widely used.

Although antibiotic treatment can be effective in patients with uncomplicated appendicitis (box 1), some will still require surgery, which may be more extensive if antibiotics fail and surgery is delayed, and there is a substantial risk of recurrence.910111213 Patients need to be informed about treatment alternatives and made aware of all the relevant risks so that they can decide what is most suitable for their circumstances. However, we argue that antibiotics should not be presented as an equivalent treatment to surgery when explaining therapeutic options.

Box 1

Uncomplicated appendicitis

  • Uncomplicated appendicitis is acute inflammation of the appendix without appendicolith, perforation, abscess, pelvic inflammatory changes, or suspicion of tumour

  • Diagnosis is based on computed tomography or intraoperative findings

  • Lack of standardised definitions about the features of complicated appendicitis may lead to variability in reported outcomes of patients with acute complicated or uncomplicated appendicitis

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Evidence supports appendicectomy as firstline therapy

Operative risk is …

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