Recipients of blood or blood products “at vCJD risk”
BMJ 2004; 328 doi: https://doi.org/10.1136/bmj.328.7432.118 (Published 15 January 2004) Cite this as: BMJ 2004;328:118Data supplement
- Recipients of blood or blood products "at vCJD risk"
Sheila M Bird, MRC Biostatistics Unit, CAMBRIDGE CB2 2SR
Until more is known about bloodborne transmission of vCJD, we must hope for the best, protect against the worst, and collate the data that are necessary to better calibrate risk. In particular, recipients’ agreement in life should be sought for informative investigations, including neuropathological or tonsillar, to be performed postmortem so that key data are not lost that could reduce uncertainty for others unwillingly at risk of vCJD.
vCJD donor:Five year calendar period of birth [19´ 0-19´ 4 or 19´ 5-19´ 9]
Sex
Codon 129 phenotype (to date: all methionine homozygote)
Month and year of vCJD infected donation
Month and year of vCJD recipient’s "vCJD infected blood transfusion" from donor
Number and type of at-vCJD risk units transfused (had red cells been leucodepleted?)
Month and year of vCJD donor’s
i) vCJD onset
ii) Notification to National CJD Surveillance Unit
iii) Death
iv) vCJD diagnosis
vCJD recipient:
5-year calendar period of birth [19´ 0-19´ 4 or 19´ 5-19´ 9]
Sex
Codon 129 phenotype (whether vCJD recipient is methionine homozygote)
Month and year of vCJD recipient’s
i) vCJD onset
iia) Notification to National CJD Surveillance Unit
iib) Identification as recipient of blood transfusion/products from a donor who subsequently developed vCJD
iii) Death, and
iv) vCJD diagnosis
For each known other recipient (of potentially vCJD incubating blood transfusion or products from same vCJD donor):
Five year calendar period of birth [19´ 0-19´ 4 or 19´ 5-19´ 9] of recipient at risk of vCJD
Sex of recipient at risk of vCJD
Codon 129 phenotype (whether recipient of potentially vCJD incubating blood transfusion or products is methionine homozygote)
Month and year of receipt of potentially vCJD infected blood transfusion or products
Survival status of recipient (if deceased: month and year of death and whether postmortem or tonsil biopsywas performed)
Status of recipient re stored operative tissue testable for abnormal PrPSC (month and year of operation, location of testable operative tissue)
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