General Practice Statistics Notes: One and two sided tests of significance BMJ 1994; 309 doi: https://doi.org/10.1136/bmj.309.6949.248 (Published 23 July 1994) Cite this as: BMJ 1994;309:248 Article Related content Metrics Responses Peer review Related articles Letter One and two sided tests of significance Statsitical hypothesis should be brought into line with clinial hypothesis Published: 01 October 1994; BMJ 309 doi:10.1136/bmj.309.6958.873a Cited by... Why perform a priori sample size calculation?Fulltext PDF Research questions, hypotheses and objectivesFulltext PDF Response to Comment on "Reassessment of the Role of Mut S Homolog 5 in Ig Class Switch Recombination Shows Lack of Involvement in cis- and trans-Switching"Fulltext PDF Defending the Rationale for the Two-Tailed Test in Clinical ResearchFulltext PDF One and two sided tests of significance Statsitical hypothesis should be brought into line with clinial hypothesisFulltext PDF