Strategy to identify people for cholesterol measurement Adults (aged 30-74 years with no previous history of MI, stroke, angina) identified for cholesterol measurement People at ≥ 15% risk identified No of cholesterol measurements needed to identify one person at ≥ 15% risk (yield) National service framework criteria 43.4 (42.2 to 44.6) 81.2 (80.2 to 82.2) 3.2 Sheffield tables 73.1 (72.0 to 74.2) 99.91 (99.83 to 99.99) 4.4 All people aged ≥50 years 46.3 (45.1 to 47.5) 92.8 (92.1 to 93.4) 2.9 All people whose estimated risk calculated by using fixed TC:HDL (5.3 in men and 4.6 in women) is ≥15% 17.8 (16.8 to 18.7) 75.9 (74.8 to 76.9) 1.4 National service framework criteria plus Sheffield tables 78.4 (77.4 to 79.4) 99.91 (99.83 to 99.99) 4.7 National service framework criteria plus all those ≥50 years 60.9 (59.8 to 62.2) 97.5 (97.2 to 97.9) 3.7 National service framework criteria plus all those whose estimated risk calculated by using fixed TC:HDL is ≥15% 46.8 (45.5 to 48.0) 93.4 (92.7 to 93.9) 3.0

MI=myocardial infarction; TC:HDL=ratio of total cholesterol to high density lipoprotein cholesterol.