Table 3
Associations between sensitisation to moulds and severity of asthma (% of sensitised participants by severity and odds ratios (95% confidence interval) for moderate versus mild asthma and severe versus mild asthma)
| Current asthma | ||||
|---|---|---|---|---|
| Mild (n=564) | Moderate (n=333) | Severe (n=235) | P value | |
| Alternaria alternata | ||||
| % sensitised | 8.9 | 13.8 | 16.6 | <0.001 |
| Unadjusted odds ratio | 1 | 1.64 (1.08 to 2.52) | 2.05 (1.31 to 3.21) | <0.001 |
| Multivariate adjusted odds ratio* | 1 | 1.61 (1.04 to 2.50) | 2.03 (1.26 to 3.27) | <0.001 |
| Cladosporium herbarum | ||||
| % sensitised | 3.9 | 5.4 | 11.1 | <0.001 |
| Unadjusted odds ratio | 1 | 1.41 (0.74 to 2.66) | 3.07 (1.70 to 5.50) | <0.001 |
| Multivariate adjusted odds ratio* | 1 | 1.21 (0.62 to 2.36) | 3.20 (1.72 to 5.94) | <0.001 |
| Either mould | ||||
| % sensitised | 10.8 | 15.9 | 22.1 | <0.001 |
| Unadjusted odds ratio | 1 | 1.56 (1.05 to 2.32) | 2.34 (1.56 to 3.52) | <0.001 |
| Multivariate adjusted odds ratio* | 1 | 1.48 (0.98 to 2.24) | 2.34 (1.52 to 3.60) | <0.001 |
↵* Adjusted for age, sex, smoking, passive smoking, parental history of asthma, and region.
