Table 3 Incidence of admissions to hospital for hepatopathy, and rate ratios among current users of nimesulide and other non-steroidal anti-inflammatory drugs by severity of hepatopathy

Events
No of events*
Rate per 100 000 person years{dagger}
Adjusted rate ratio{ddagger} (95% CI)
All hepatopathies (n=42)



Nimesulide
17
35.2
1.3 (0.7 to 2.3)
Other non-steroidal anti-inflammatory drugs
29
28.3
1
Liver injury (n=33)§



Nimesulide
16
33.1
1.7 (0.9 to 3.3)
Other non-steroidal anti-inflammatory drugs
20
19.5
1
More severe liver injury (n=28)



Nimesulide
14
29.0
1.9 (1.1 to 3.8)
Other non-steroidal anti-inflammatory drugs
16
15.6
1

All hepatopathies includes abnormal liver function and liver injury.

* Patients who received both nimesulide and other non-steroidal anti-inflammatory drugs during current period (mixed use) are counted in both groups.

{dagger} Person years of exposure to nimesulide and other non-steroidal anti-inflammatory drugs are 48 294 and 102 536, respectively.

{ddagger} Adjusted for age and sex.

§ Twice upper limit of normal range

Five times upper limit of normal range