Table 2 Incidence of admissions to hospital for hepatopathy, and rate ratios
according to drug use, age, and sex
|
|
|
All hepatopathies
|
Liver injury
|
Characteristic
|
Person years
|
No of events
|
Rates per 100 000 person years
|
Adjusted rate
ratio*
(95% CI)
|
No of events
|
Rates per 100 000 person years
|
Adjusted rate
ratio*
(95% CI)
|
Category of use:
|
|
|
|
|
|
|
|
Current
|
140 836
|
42
|
29.8
|
1.4 (1.0 to 2.1)
|
33
|
23.4
|
1.4 (0.9 to 2.1)
|
Recent
|
254 467
|
65
|
25.5
|
1.4 (1.0 to 2.0)
|
46
|
18.1
|
1.3 (0.9 to 1.9)
|
Past
|
378 433
|
69
|
18.2
|
1
|
56
|
14.8
|
1
|
Age (years):
|
|
|
|
|
|
|
|
<45
|
150 849
|
11
|
7.3
|
1
|
9
|
6.0
|
1
|
45-54
|
127 284
|
14
|
11.0
|
1.5 (0.7 to 1.3)
|
10
|
7.9
|
1.3 (0.7 to 3.3)
|
55-64
|
156 046
|
41
|
26.3
|
3.6 (1.9 to 7.4)
|
29
|
18.6
|
3.1 (1.5 to 6.6)
|
65-74
|
192 993
|
45
|
23.3
|
3.2 (1.6 to 6.1)
|
34
|
17.6
|
2.9 (1.4 to 6.1)
|
 75
|
146 542
|
65
|
44.4
|
5.7 (3.0 to 11.0)
|
53
|
36.2
|
5.6 (2.8 to 11.0)
|
Sex:
|
|
|
|
|
|
|
|
Male
|
311 531
|
88
|
28.2
|
1.5 (1.2 to 2.2)
|
68
|
21.8
|
1.7 (1.2 to 2.3)
|
Female
|
462 182
|
88
|
19.0
|
1
|
67
|
14.5
|
1
|
|
* Rate ratios for non-steroidal anti-inflammatory drug use adjusted for age
and sex; rate ratios for age adjusted for sex and current use of non-steroidal
anti-inflammatory drug; rate ratios for sex adjusted for age and current use
of non-steroidal anti-inflammatory drug.